Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424202 | 0.74 | CA2 (0.46) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL3924748 | 0.72 | CA2 (0.43) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL18663420 | 0.72 | CA2 (0.43) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL15116346 | 0.72 | CA1 (0.43) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL15116350 | 0.69 | CA1 (0.40) | CA1CA2EPHX1 | |
| SCHEMBL4457449 | 0.65 | CA2 (0.56) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL37874 | 0.65 | CA2 (0.56) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL28511453 | 0.65 | CA2 (0.56) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL23886640 | 0.63 | CA2 (0.53) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL9982903 | 0.63 | CA2 (0.53) | CA1CA2CA7CA13EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |