Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 6/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465520 | 0.91 | TBXA2R (0.58) | TBXA2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10462980 | 0.91 | TBXA2R (0.54) | TBXA2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10464736 | 0.87 | TBXA2R (0.44) | TBXA2RPTGDRPTGDR2MEN1KMT2A | |
| SCHEMBL10464046 | 0.83 | TBXA2R (0.67) | TBXA2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10464527 | 0.83 | TBXA2R (0.53) | TBXA2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10464515 | 0.83 | TBXA2R (0.53) | TBXA2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10690261 | 0.82 | PSEN1 (0.49) | TBXA2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10357320 | 0.81 | CA1 (0.52) | TBXA2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10463083 | 0.80 | TBXA2R (0.51) | TBXA2RHDAC8CA1CA2MEN1 | |
| SCHEMBL10465047 | 0.80 | TBXA2R (0.51) | TBXA2RCA1CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921998-A | ANTICOAGULANTS, ANTIISCHEMIC AGENTS, ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| US-4868331-A | ANTICOAGULANTS, ANTIATHEROSCLEROTIC, ANTIISCHEMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |