Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | APEX1 | P27695 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465746 | 0.87 | PRKCI (0.46) | MAPTKDM4ETDP1ALDH1A1PRKCI | |
| SCHEMBL30988826 | 0.85 | CYP3A4 (0.38) | MAPTKDM4EAPEX1RECQLBLM | |
| SCHEMBL29256510 | 0.85 | CYP3A4 (0.38) | MAPTKDM4EAPEX1RECQLBLM | |
| SCHEMBL10467017 | 0.85 | BLM (0.47) | MAPTKDM4EAPEX1RECQLBLM | |
| SCHEMBL11490380 | 0.85 | BLM (0.47) | MAPTKDM4EAPEX1RECQLBLM | |
| Hydrochloric Acid SCHEMBL11482126 | 0.84 | BLM (0.46) | MAPTKDM4EAPEX1RECQLBLM | |
| Hydrochloric Acid SCHEMBL11482129 | 0.84 | BLM (0.46) | MAPTKDM4EAPEX1RECQLBLM | |
| Hydrochloric Acid SCHEMBL11483484 | 0.84 | BLM (0.46) | MAPTKDM4EAPEX1RECQLBLM | |
| SCHEMBL10467041 | 0.84 | MAPT (0.37) | MAPTKDM4EAPEX1RECQLBLM | |
| SCHEMBL5404733 | 0.78 | MAPT (0.40) | MAPTKDM4EAPEX1RECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960783-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |