Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30988826 | 1.00 | CYP3A4 (0.38) | CYP3A4TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL10467017 | 0.87 | BLM (0.47) | CYP3A4TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL11490380 | 0.87 | BLM (0.47) | CYP3A4TSHRMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11482129 | 0.85 | BLM (0.46) | CYP3A4TSHRMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11482126 | 0.85 | BLM (0.46) | CYP3A4TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL10465744 | 0.85 | MAPT (0.37) | CYP3A4MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL10467041 | 0.85 | MAPT (0.37) | MAPTKDM4EALDH1A1APEX1RECQL | |
| Hydrochloric Acid SCHEMBL11483484 | 0.85 | BLM (0.46) | CYP3A4TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL10467265 | 0.82 | MAPT (0.41) | CYP3A4MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL5404733 | 0.79 | MAPT (0.40) | CYP3A4MAPTKDM4EALDH1A1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118340754-A | Compound for treating heart failure and related diseases and application thereof | 源道医药(苏州)有限公司 | 2024-07-16 | — | — | CN | disclosed |