Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10333504 | 0.78 | HTT (0.53) | MAPTHTTLMNAPKMPOLB | |
| SCHEMBL6949649 | 0.78 | MAPT (0.48) | MAPTHTTLMNAPKMPOLB | |
| SCHEMBL8848381 | 0.78 | ALDH1A1 (0.49) | MAPTHTTPOLBTSHRRAB9A | |
| SCHEMBL11199645 | 0.77 | SMN1; SMN2 (0.50) | MAPTHTTLMNAPOLBNPC1 | |
| SCHEMBL11357363 | 0.76 | MAPT (0.46) | MAPTHTTLMNAPKMPOLB | |
| SCHEMBL10680117 | 0.76 | MAPT (0.46) | MAPTHTTLMNAPKMPOLB | |
| SCHEMBL29226359 | 0.76 | ALDH1A1 (0.52) | MAPTHTTLMNAPKMPOLB | |
| SCHEMBL10390727 | 0.76 | TSHR (0.52) | MAPTHTTLMNAPKMPOLB | |
| SCHEMBL7293623 | 0.75 | HTT (0.63) | MAPTHTTLMNAPKMPOLB | |
| SCHEMBL11440981 | 0.75 | MAPT (0.60) | MAPTLMNAPOLBTSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975464-A | ADMINISTERING DERIVATIVES OF P-GUANIDINOBENZOIC ACID | IMAKI KATSUHIRO (JP) | 1990-12-04 | — | — | US | disclosed |
| US-4957934-A | AROMATASE INHIBITORS, TREATMENT OF STEROID HORMONE DEPENDENT DISEASES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-09-18 | — | — | US | disclosed |
| EP-0299684-A1 | Heterocyclic Compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-18 | — | — | EP | disclosed |