Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465614 | 0.84 | POLB (0.44) | MAP4K4MAOAMAOBALDH1A1NPSR1 | |
| SCHEMBL11530819 | 0.81 | MAP4K4 (0.47) | MAP4K4SSTR4PPARAMAOAMAOB | |
| SCHEMBL10518546 | 0.78 | SLC6A2 (0.46) | SSTR4PPARACYP19A1LMNANFKB1 | |
| SCHEMBL10465341 | 0.78 | PPARA (0.57) | MAP4K4PPARACYP19A1ALDH1A1LMNA | |
| SCHEMBL10390840 | 0.76 | SSTR4 (0.52) | MAP4K4SSTR4PPARAMAOAMAOB | |
| SCHEMBL21748609 | 0.76 | MAP4K4 (0.62) | MAP4K4SSTR4PPARAMAOAMAOB | |
| SCHEMBL10465605 | 0.75 | MEN1 (0.41) | CYP19A1NPC1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10466908 | 0.74 | PPARA (0.43) | PPARAALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL10457874 | 0.73 | CYP19A1 (0.47) | MAP4K4CYP19A1CYP3A4MEN1KMT2A | |
| SCHEMBL21748570 | 0.73 | SSTR4 (0.53) | MAP4K4SSTR4PPARAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4877446-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-31 | — | — | US | claimed |
| US-4939155-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |
| US-4877446-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-31 | — | — | US | disclosed |
| EP-0277520-A2 | Parasiticide on a pyrimidine derivative basis | BAYER AG (DE) | 1988-08-10 | — | — | EP | disclosed |