Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | FABP2 | P12104 | 2/20 | 0.54 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10466908 | 0.86 | PPARA (0.43) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL9288749 | 0.85 | ABL1 (0.51) | KCNH2 | |
| SCHEMBL9772021 | 0.84 | CYP1A2 (0.63) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL10554594 | 0.84 | PPARA (0.68) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL10465969 | 0.78 | MAP4K4 (0.47) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL10722877 | 0.75 | CYP1A2 (0.53) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL9372364 | 0.73 | PPARA (0.72) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL135713 | 0.73 | PPARA (0.72) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| Clofibric Acid SCHEMBL102826 | 0.73 | PPARA (1.00) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 | |
| Clofibric Acid SCHEMBL2227936 | 0.73 | PPARA (1.00) | PPARACYP1A2CYP3A4CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277520-A2 | Parasiticide on a pyrimidine derivative basis | BAYER AG (DE) | 1988-08-10 | — | — | EP | claimed |
| US-4939155-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |
| US-4877446-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-31 | — | — | US | disclosed |
| EP-0277520-A2 | Parasiticide on a pyrimidine derivative basis | BAYER AG (DE) | 1988-08-10 | — | — | EP | disclosed |