Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GABRE | P78334 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.38 |
| ▸ | ASPH | Q12797 | 3/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467327 | 0.87 | KDM4E (0.43) | KDM4EKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL10466213 | 0.82 | KDM4E (0.46) | KDM4EKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL10465936 | 0.81 | CYP1A2 (0.48) | KDM4EKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL10465596 | 0.78 | KDM4E (0.44) | KDM4EASPHKDM8CYP1A2KDM6B | |
| SCHEMBL10467539 | 0.78 | KDM4E (0.42) | KDM4EKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL10465993 | 0.77 | KDM4E (0.41) | KDM4EKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL10465783 | 0.77 | KDM4E (0.41) | KDM4EKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL10464541 | 0.76 | KDM4E (0.43) | KDM4EKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL10466175 | 0.76 | KDM4E (0.43) | KDM4EKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL338428 | 0.74 | CYP1A2 (0.46) | KDM4EKMT2ACYP1A2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968803-A | FLUORINE AS OXIDANT | ALLIED-SIGNAL INC. (US) | 1990-11-06 | — | — | US | disclosed |
| US-4957934-A | AROMATASE INHIBITORS, TREATMENT OF STEROID HORMONE DEPENDENT DISEASES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-09-18 | — | — | US | disclosed |