SCHEMBL10465993

SCHEMBL10465993

O=C(O)c1cnc2c(Br)c(C(=O)O)c(Br)c(Br)c2c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
KMT2A Q03164 1/20 0.41
HAVCR2 Q8TDQ0 1/20 0.33
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRB2 P47870 2/20 0.32
GABRA4 P48169 2/20 0.32
GABRE P78334 2/20 0.32
GABRA6 Q16445 2/20 0.32
GABRG1 Q8N1C3 2/20 0.32
GABRG3 Q99928 2/20 0.32
GABRQ Q9UN88 2/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10465783 0.86 KDM4E (0.41) KDM4EKMT2AHAVCR2GABRPGABRD
SCHEMBL10465989 0.77 KDM4E (0.44) KDM4EKMT2AHAVCR2GABRPGABRD
SCHEMBL10465936 0.77 CYP1A2 (0.48) KDM4EKMT2AHAVCR2GABRPGABRD
SCHEMBL10466213 0.74 KDM4E (0.46) KDM4EKMT2AHAVCR2GABRPGABRD
SCHEMBL10467327 0.71 KDM4E (0.43) KDM4EKMT2AHAVCR2GABRPGABRD
SCHEMBL10467539 0.70 KDM4E (0.42) KDM4EKMT2AHAVCR2GABRPGABRD
SCHEMBL10464792 0.68 KDM4E (0.40) KDM4EKMT2AGABRPGABRDGABRA1
SCHEMBL1035933 0.67 CYP1A2 (0.47) KDM4EKMT2ATSHRALDH1A1CYP1A2
SCHEMBL10465988 0.67 PRNP (0.41) KDM4EKMT2AHAVCR2ALDH1A1HPGD
SCHEMBL10464638 0.66 KDM4E (0.44) KDM4EKMT2AGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230123928-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-04-20 US disclosed
US-20160330960-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2016-11-17 US disclosed
US-9439434-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2016-09-13 US disclosed
US-20140155261-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2014-06-05 US disclosed
US-4968803-A FLUORINE AS OXIDANT ALLIED-SIGNAL INC. (US) 1990-11-06 US disclosed
US-4505916-A TRANQUILIZERS PHARMINDUSTRIE (FR) 1985-03-19 US disclosed
US-4433150-A HYPNBOTICS, ANTICONVULSANTS, TRANQUILIZERS, ANTIDEPRESSANTS, SEDATIVES, ANTIARRHYTHMIA AGENTS PHARMINDUSTRIE (FR) 1984-02-21 US disclosed
US-4402961-A Derivatives of 1-(2-,3- or 4-quinolyl)-2- or -3-(2- or 3-piperidyl or -pyrrolidinyl) ethanone or propanone, and their utilization as antiarrhythmics, anticonvulsivants and for the treatment of anxiety PHARMINDUSTRIE (FR) 1983-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160330960-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 KDM4E 402/4885KMT2A 794/4885HAVCR2 1893/4885
US-20140155261-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 KDM4E 402/4885KMT2A 794/4885HAVCR2 1893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.