SCHEMBL10467477

SCHEMBL10467477

O=C(Oc1ccccc1)c1ccc(-n2nnnc2[S])cc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.51
MAPT P10636 5/20 0.45
ALDH1A1 P00352 6/20 0.44
HPGD P15428 2/20 0.44
HTT P42858 1/20 0.44
PARP10 Q53GL7 1/20 0.43
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43
TMPRSS15 P98073 1/20 0.43
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10467099 0.95 KMT2A (0.58) KMT2AMAPTALDH1A1PARP10RAB9A
SCHEMBL10468239 0.86 MAPK1 (0.53) KMT2AMAPTALDH1A1HPGDHTT
SCHEMBL6152799 0.84 KMT2A (0.51) KMT2AMAPTALDH1A1HPGDHTT
SCHEMBL11331769 0.80 ALDH1A1 (0.66) KMT2AMAPTALDH1A1HPGDHTT
SCHEMBL10467593 0.79 HPGD (0.52) KMT2AMAPTALDH1A1HPGDHTT
SCHEMBL6153023 0.78 KMT2A (0.58) KMT2AMAPTALDH1A1HPGDHTT
Hydrochloric Acid SCHEMBL8094637 0.74 ALDH1A1 (0.52) KMT2AMAPTALDH1A1HPGDHTT
SCHEMBL70034 0.73 PARP10 (0.70) KMT2AMAPTALDH1A1HPGDPARP10
SCHEMBL11128116 0.70 KMT2A (0.48) KMT2AMAPTALDH1A1HPGDPARP10
SCHEMBL6153223 0.70 MAPK1 (0.53) KMT2AMAPTALDH1A1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4950764-A HERBICIDES, BACTERICIDES, ANALGESICS, ANTIINFLAMMATORY AGENT FUJI PHOTO FILM CO., LTD. (JP) 1990-08-21 US disclosed