SCHEMBL104678

SCHEMBL104678

O=C(O)CNCc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=S)[nH]c1=O

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.48
SLC28A1 O00337 1/20 0.43
SLC28A2 O43868 1/20 0.43
SLC29A1 Q99808 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43
TK2 O00142 2/20 0.43
DNPH1 O43598 1/20 0.41
P2RY2 P41231 1/20 0.41
CDK1 P06493 1/20 0.40
HPGD P15428 1/20 0.39
MAPT P10636 1/20 0.39
CDA P32320 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26369647 1.00 PYGM (0.48) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL104679 1.00 PYGM (0.48) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL17721687 0.90 PYGM (0.47) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL18512960 0.89 PYGM (0.58) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL41270 0.89 PYGM (0.58) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL63573 0.89 PYGM (0.58) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL14853731 0.89 PYGM (0.58) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL18573807 0.89 PYGM (0.58) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL18503558 0.89 PYGM (0.58) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL3805743 0.88 PYGM (0.45) PYGMSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18360 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109727-A1 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2026-04-23 US claimed
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
EP-4659246-A1 ELECTROCHEMICAL SYNTHESIS WITH REDOX STABLE NUCLEOTIDES Atlas Data Storage, Inc. (US) 2025-12-10 EP claimed
US-20250368986-A1 ELECTROCHEMICAL SYNTHESIS WITH REDOX STABLE NUCLEOTIDES ATLAS DATA STORAGE INC (US) 2025-12-04 US claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 EP claimed
US-20250304965-A1 DOUBLE-STRANDED RNA MOLECULE AND PHARMACEUTICAL USE THEREOF MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-10-02 US claimed
US-20250295744-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS BioNTech SE (DE) 2025-09-25 US claimed
US-20250277223-A1 METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISEASES IMCYSE SA (BE) 2025-09-04 US claimed
EP-4598935-A2 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2025-08-13 EP claimed
US-6706691-B1 BIOAVAILABILITY OF COMPOSITIONS METABOLIZED BY THE GUT P450 ISOZYMES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2004-03-16 US claimed
EP-1308511-A1 Use of angiopoietin-like 1 and angiopoietin-like 2 nucleic acids and proteins for the treatment of blood-related disorders and defects in vasculature. Mermaid Pharmaceuticals GmbH (DE) 2003-05-07 EP claimed
EP-1295130-A2 NIMR COMPOSITIONS AND THEIR METHODS OF USE TRUSTEES OF TUFTS COLLEGE (US) 2003-03-26 EP claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
WO-2001070776-A2 NIMR COMPOSITIONS AND THEIR METHODS OF USE TRUSTEES OF TUFTS COLLEGE (US) 2001-09-27 WO claimed
US-5998596-A Inhibition of protein kinase activity by aptameric action of oligonucleotides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-07 US claimed
WO-1998042723-A9 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS 1999-03-04 WO claimed
EP-0795029-A1 CHEMICAL LABELLING OF OBJECTS Pabio (NO) 1997-09-17 EP claimed
WO-1996017954-A1 CHEMICAL LABELLING OF OBJECTS PABIO (DK) 1996-06-13 WO claimed
US-5486603-A Oligonucleotide having enhanced binding affinity GILEAD SCIENCES, INC. (US) 1996-01-23 US claimed