Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 2/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 2/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467549 | 0.93 | GPR84 (0.50) | GPR84HTR2ACA2SLC6A4CCKBR | |
| SCHEMBL10467558 | 0.93 | GPR84 (0.50) | GPR84HTR2ACA2SLC6A4CCKBR | |
| SCHEMBL10468796 | 0.92 | HDAC3 (0.51) | GPR84HTR2ACA2SLC6A4CCKBR | |
| SCHEMBL10467230 | 0.91 | GPR84 (0.48) | GPR84HTR2ACA2SLC6A4CCKBR | |
| SCHEMBL10468784 | 0.91 | GPR84 (0.48) | GPR84HTR2ACA2SLC6A4CCKBR | |
| SCHEMBL10467137 | 0.91 | HDAC3 (0.48) | GPR84HTR2ACA2SLC6A4CCKBR | |
| SCHEMBL10569279 | 0.91 | GPR84 (0.48) | GPR84HTR2ACA2SLC6A4CCKBR | |
| SCHEMBL10469080 | 0.89 | GPR84 (0.47) | GPR84HTR2ACA2SLC6A4CCKBR | |
| SCHEMBL10467635 | 0.88 | GPR84 (0.46) | GPR84HTR2ACA2SLC6A4CCKBR | |
| SCHEMBL10466784 | 0.88 | GPR84 (0.46) | GPR84HTR2ACA2SLC6A4CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940709-A | PLATELET ACTIVATING FACTOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| EP-0181152-B1 | PIPERAZINE COMPOUND AS PAF-ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4806538-A | ANTICOAGULANT, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-21 | — | — | US | disclosed |