SCHEMBL1046902

SCHEMBL1046902

CCCCCCCCOc1cc(C#N)ccc1-c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.57
CYP11B1 P15538 2/20 0.57
CYP11B2 P19099 2/20 0.57
PTGDR2 Q9Y5Y4 1/20 0.47
SOAT1 P35610 1/20 0.47
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
KDM4E B2RXH2 3/20 0.46
HTT P42858 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
PTPN11 Q06124 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
PTPN1 P18031 1/20 0.43
GRM5 P41594 1/20 0.42
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LTA4H P09960 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5310305 1.00 CYP19A1 (0.57) CYP19A1CYP11B1CYP11B2PTGDR2SOAT1
SCHEMBL28337686 1.00 CYP19A1 (0.57) CYP19A1CYP11B1CYP11B2PTGDR2SOAT1
SCHEMBL9206760 0.99 CYP11B1 (0.58) CYP19A1CYP11B1CYP11B2PTGDR2SOAT1
SCHEMBL29678079 0.99 CYP11B1 (0.58) CYP19A1CYP11B1CYP11B2PTGDR2SOAT1
SCHEMBL9213631 0.90 CYP11B1 (0.61) CYP19A1CYP11B1CYP11B2PTGDR2KDM4E
SCHEMBL15540307 0.86 SOAT1 (0.47) CYP19A1CYP11B1CYP11B2SOAT1ALDH1A1
SCHEMBL2572668 0.85 CYP19A1 (0.61) CYP19A1CYP11B1CYP11B2PTGDR2PTPN1
SCHEMBL1046904 0.83 KDM4E (0.51) CYP19A1ALDH1A1HPGDKDM4EHTT
SCHEMBL28337685 0.83 KDM4E (0.51) CYP19A1ALDH1A1HPGDKDM4EHTT
SCHEMBL5310309 0.83 KDM4E (0.51) CYP19A1ALDH1A1HPGDKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114863791-A Multiple anti-counterfeit label and preparation method thereof 中国科学技术大学 2022-08-05 CN claimed
CN-114686049-A Printing ink with multiple anti-counterfeiting effects and preparation method and application thereof 中国科学技术大学 2022-07-01 CN claimed
CN-110088649-B Adjusting device in sunlight simulation lighting system 科勒克斯有限责任公司 2022-08-09 CN disclosed
CN-114863791-A Multiple anti-counterfeit label and preparation method thereof 中国科学技术大学 2022-08-05 CN disclosed
CN-114686049-A Printing ink with multiple anti-counterfeiting effects and preparation method and application thereof 中国科学技术大学 2022-07-01 CN disclosed
CN-110527523-A A kind of dual imaging storage material, preparation method and application UNIV HUAZHONG SCIENCE TECH 2019-12-03 CN disclosed
CN-104460037-B The method and apparatus of Ophthalmoligic instrument including cycloid aligned liquid-crystal layer 庄臣及庄臣视力保护公司 2018-09-28 CN disclosed
EP-1851585-B1 ADAPTIVE ELECTRO-ACTIVE LENS WITH VARIABLE FOCAL LENGTH JOHNSON & JOHNSON VISION CARE (US) 2018-06-27 EP disclosed
US-9958705-B2 Electro-active opthalmic lens having an optical power blending region E-VISION SMART OPTICS, INC. (US) 2018-05-01 US disclosed
US-20170307905-A1 Electro-Active Opthalmic Lens Having an Optical Power Blending Region E-VISION SMART OPTICS INC (US) 2017-10-26 US disclosed
US-9778489-B2 Electro-active spectacles E-VISION SMART OPTICS, INC. (US) 2017-10-03 US disclosed
WO-2001001848-A1 METHOD FOR REFRACTING AND DISPENSING ELECTRO-ACTIVE SPECTACLES E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
WO-2001002895-A1 SYSTEM, APPARATUS, AND METHOD FOR CORRECTING VISION USING AN ELECTRO-ACTIVE LENS E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
WO-2001002897-A1 SYSTEM, APPARATUS, AND METHOD FOR CORRECTING VISION USING ELECTRO-ACTIVE SPECTACLES E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
WO-2001002896-A1 SYSTEM, APPARATUS, AND METHOD FOR REDUCING BIREFRINGENCE E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
EP-0180592-B1 LIGHT MODULATING MATERIAL COMPRISING A LIQUID CRYSTAL DISPERSION IN A SYNTHETIC RESIN MATRIX UNIV KENT STATE OHIO (US) 1995-08-02 EP disclosed
EP-0656927-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX Sniaricerche S.C.P.A. (IT) 1995-06-14 EP disclosed
EP-0238626-B1 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS UNIV KENT STATE OHIO (US) 1995-05-03 EP disclosed
EP-0144683-B1 ALIGNMENT LAYER ORIENTATION IN LIQUID CRYSTAL DISPLAYS International Business Machines Corporation (US) 1990-01-03 EP disclosed
WO-1985004262-A1 LIGHT MODULATING MATERIAL COMPRISING A LIQUID CRYSTAL DISPERSION IN A SYNTHETIC RESIN MATRIX KENT STATE UNIVERSITY (US) 1985-09-26 WO disclosed