SCHEMBL1046904

SCHEMBL1046904

CCCCCCCCOc1ccccc1-c1ccc(C#N)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.51
ALDH1A1 P00352 4/20 0.51
HPGD P15428 3/20 0.51
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
TSHR P16473 1/20 0.50
HSD17B10 Q99714 1/20 0.50
PTPN11 Q06124 1/20 0.45
ADRB2 P07550 1/20 0.44
AR P10275 2/20 0.44
MEN1 O00255 1/20 0.43
NR1I2 O75469 1/20 0.43
LMNA P02545 1/20 0.43
CHRM2 P08172 1/20 0.43
CYP3A4 P08684 1/20 0.43
ADRA2A P08913 1/20 0.43
MAPT P10636 1/20 0.43
OPRK1 P41145 1/20 0.43
HTR2B P41595 1/20 0.43
SLC6A3 Q01959 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5310309 1.00 KDM4E (0.51) KDM4EALDH1A1HPGDHTTL3MBTL1
SCHEMBL28337685 1.00 KDM4E (0.51) KDM4EALDH1A1HPGDHTTL3MBTL1
SCHEMBL9206767 0.99 KDM4E (0.49) KDM4EALDH1A1HPGDHTTL3MBTL1
SCHEMBL9213633 0.90 ADRB2 (0.48) KDM4EALDH1A1ADRB2ARMEN1
SCHEMBL15522393 0.87 AR (0.51) KDM4EALDH1A1HTTARMEN1
SCHEMBL6635341 0.86 AR (0.44) KDM4EALDH1A1ADRB2ARMEN1
SCHEMBL27786320 0.85 KDM4E (0.58) KDM4EALDH1A1L3MBTL1PTPN11ADRB2
SCHEMBL28207267 0.85 KDM4E (0.58) KDM4EALDH1A1L3MBTL1PTPN11ADRB2
SCHEMBL28141538 0.85 LTA4H (0.56) KDM4ETSHRPTPN11ADRB2MEN1
SCHEMBL28142366 0.85 LTA4H (0.56) KDM4ETSHRPTPN11ADRB2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114863791-A Multiple anti-counterfeit label and preparation method thereof 中国科学技术大学 2022-08-05 CN claimed
CN-114686049-A Printing ink with multiple anti-counterfeiting effects and preparation method and application thereof 中国科学技术大学 2022-07-01 CN claimed
CN-110088649-B Adjusting device in sunlight simulation lighting system 科勒克斯有限责任公司 2022-08-09 CN disclosed
CN-114863791-A Multiple anti-counterfeit label and preparation method thereof 中国科学技术大学 2022-08-05 CN disclosed
CN-114686049-A Printing ink with multiple anti-counterfeiting effects and preparation method and application thereof 中国科学技术大学 2022-07-01 CN disclosed
CN-110527523-A A kind of dual imaging storage material, preparation method and application UNIV HUAZHONG SCIENCE TECH 2019-12-03 CN disclosed
CN-104460037-B The method and apparatus of Ophthalmoligic instrument including cycloid aligned liquid-crystal layer 庄臣及庄臣视力保护公司 2018-09-28 CN disclosed
EP-1851585-B1 ADAPTIVE ELECTRO-ACTIVE LENS WITH VARIABLE FOCAL LENGTH JOHNSON & JOHNSON VISION CARE (US) 2018-06-27 EP disclosed
US-9958705-B2 Electro-active opthalmic lens having an optical power blending region E-VISION SMART OPTICS, INC. (US) 2018-05-01 US disclosed
US-20170307905-A1 Electro-Active Opthalmic Lens Having an Optical Power Blending Region E-VISION SMART OPTICS INC (US) 2017-10-26 US disclosed
US-9778489-B2 Electro-active spectacles E-VISION SMART OPTICS, INC. (US) 2017-10-03 US disclosed
WO-2001001848-A1 METHOD FOR REFRACTING AND DISPENSING ELECTRO-ACTIVE SPECTACLES E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
WO-2001002895-A1 SYSTEM, APPARATUS, AND METHOD FOR CORRECTING VISION USING AN ELECTRO-ACTIVE LENS E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
WO-2001002897-A1 SYSTEM, APPARATUS, AND METHOD FOR CORRECTING VISION USING ELECTRO-ACTIVE SPECTACLES E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
WO-2001002896-A1 SYSTEM, APPARATUS, AND METHOD FOR REDUCING BIREFRINGENCE E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
EP-0180592-B1 LIGHT MODULATING MATERIAL COMPRISING A LIQUID CRYSTAL DISPERSION IN A SYNTHETIC RESIN MATRIX UNIV KENT STATE OHIO (US) 1995-08-02 EP disclosed
EP-0656927-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX Sniaricerche S.C.P.A. (IT) 1995-06-14 EP disclosed
EP-0238626-B1 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS UNIV KENT STATE OHIO (US) 1995-05-03 EP disclosed
EP-0144683-B1 ALIGNMENT LAYER ORIENTATION IN LIQUID CRYSTAL DISPLAYS International Business Machines Corporation (US) 1990-01-03 EP disclosed
WO-1985004262-A1 LIGHT MODULATING MATERIAL COMPRISING A LIQUID CRYSTAL DISPERSION IN A SYNTHETIC RESIN MATRIX KENT STATE UNIVERSITY (US) 1985-09-26 WO disclosed