Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 5/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10470472 | 0.99 | CYP2D6 (0.36) | CYP2D6CYP1A2CYP3A4CYP2C19STAT6 | |
| SCHEMBL10470625 | 0.99 | CYP2D6 (0.36) | CYP2D6CYP1A2CYP3A4CYP2C19STAT6 | |
| SCHEMBL28769022 | 0.90 | LOXL2 (0.34) | CYP2D6CYP1A2CYP3A4CYP2C19STAT6 | |
| SCHEMBL27684044 | 0.88 | LOXL2 (0.33) | CYP2D6CYP1A2CYP3A4CYP2C19STAT6 | |
| SCHEMBL10469238 | 0.85 | PRKDC (0.33) | CYP2D6CYP1A2CYP3A4CYP2C19STAT6 | |
| SCHEMBL10470040 | 0.84 | PRKDC (0.33) | CYP2D6CYP1A2CYP3A4CYP2C19STAT6 | |
| SCHEMBL10469276 | 0.84 | PRKDC (0.33) | CYP2D6CYP1A2CYP3A4CYP2C19STAT6 | |
| SCHEMBL10469136 | 0.79 | CDK1 (0.36) | CDK1CCNB1SSTR2SSTR4 | |
| SCHEMBL9160788 | 0.74 | CYP1A2 (0.40) | CYP2D6CYP1A2CYP3A4CYP2C19STAT6 | |
| SCHEMBL27702776 | 0.72 | SSTR2 (0.35) | CDK1CCNB1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904690-A | Chromone derivatives useful as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0283761-A1 | Chromone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |