Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467887 | 0.84 | KIF11 (0.46) | EPHX2LTA4HSCN8ASCN10AKIF11 | |
| SCHEMBL2091154 | 0.82 | TSHR (0.42) | SLC6A2SLC6A4SLC6A3LTA4HRIPK1 | |
| SCHEMBL4463853 | 0.81 | SCN5A (0.34) | SLC6A2SLC6A4SLC6A3NOTUMSCN8A | |
| SCHEMBL5322056 | 0.81 | SCN9A (0.38) | FFAR4KIF11GRIN2B | |
| SCHEMBL6573031 | 0.81 | FFAR4 (0.40) | ACP1FFAR4SERPINE1NOTUMAURKA | |
| SCHEMBL10466953 | 0.79 | SLC7A5 (0.38) | SLC6A2SLC6A4SLC6A3EPHX2LTA4H | |
| SCHEMBL10469324 | 0.78 | GAA (0.45) | SLC6A2SLC6A4SLC6A3LTA4HMAPK14 | |
| SCHEMBL16720386 | 0.77 | MAPT (0.42) | EPHX2SERPINE1NOTUMAURKATPX2 | |
| SCHEMBL7683503 | 0.76 | MRGPRX1 (0.33) | SLC6A2SLC6A4SLC6A3EPHX2FFAR4 | |
| SCHEMBL16720311 | 0.75 | NOTUM (0.41) | LTA4HNOTUMMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975451-A | Insecticidal cyclopropyl di(aryl) 2-butenes | FMC CORPORATION (US) | 1990-12-04 | — | — | US | disclosed |