Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.79 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.72 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.68 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469550 | 1.00 | JUN (0.79) | JUNNFKB1ABCG2PDE4APDE4B | |
| SCHEMBL15932967 | 0.89 | JUN (0.68) | JUNNFKB1ABCG2PDE4APDE4B | |
| SCHEMBL5598598 | 0.88 | JUN (1.00) | JUNNFKB1ABCG2PDE4APDE4B | |
| SCHEMBL5598600 | 0.88 | JUN (1.00) | JUNNFKB1ABCG2PDE4APDE4B | |
| SCHEMBL10467161 | 0.87 | MAPT (0.79) | JUNNFKB1TDP1KDM4EMAPT | |
| SCHEMBL529637 | 0.87 | JUN (0.79) | JUNNFKB1ABCG2PDE4APDE4B | |
| SCHEMBL529638 | 0.87 | JUN (0.79) | JUNNFKB1ABCG2PDE4APDE4B | |
| SCHEMBL10467163 | 0.87 | MAPT (0.79) | JUNNFKB1TDP1KDM4EMAPT | |
| SCHEMBL29814346 | 0.87 | JUN (0.79) | JUNNFKB1ABCG2PDE4APDE4B | |
| SCHEMBL3209236 | 0.85 | JUN (0.77) | JUNNFKB1ABCG2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113304129-B | Application of mono-ketene monocarbonyl curcumin analogue in preparing antioxidant drugs | 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） | 2022-11-08 | — | — | CN | disclosed |
| CN-102516174-A | Poly-substituted pyrazoline compound and preparation method thereof | UNIV ZHEJIANG NORMAL | 2012-06-27 | — | — | CN | disclosed |
| US-4927958-A | ANTIULCER | HOFFMANN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0282897-A2 | Ethynyl- and ethenylstyryl ketones | F. HOFFMANN-LA ROCHE AG (CH) | 1988-09-21 | — | — | EP | disclosed |