JUN — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL541944	0.63	12/20
SCHEMBL541611	0.64	11/20
SCHEMBL330789	0.61	10/20
SCHEMBL336184	0.69	9/20
SCHEMBL336181	0.53	9/20
SCHEMBL331789	0.49	9/20
SCHEMBL458841	1.00	8/20
SCHEMBL131646	0.58	7/20
SCHEMBL423492	0.60	6/20
SCHEMBL480176	0.57	6/20
SCHEMBL473562	0.46	6/20
SCHEMBL398567	0.41	6/20
SCHEMBL79014	0.57	5/20
SCHEMBL519785	0.50	5/20
SCHEMBL20495	0.48	5/20
SCHEMBL125364	0.46	5/20
(S)-Tylophorine (SCHEMBL523625)	0.70	4/20
(+/-)-Tylophorine (SCHEMBL523626)	0.70	4/20
SCHEMBL477755	0.64	4/20
SCHEMBL453737	0.54	4/20

Clinical trials — most relevant to JUN by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Repetitive Transcranial Magnetic Stimulation in the Treatment of Phantom Limb Pain in Landmine Victims: ANTARES	PHASE3	COMPLETED
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room	PHASE2/PHASE3	COMPLETED
Clinical Evaluation of the Effect of Metformin in Sepsis	PHASE3	UNKNOWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	PHASE2	COMPLETED
Prolonged Release Pirfenidone Versus Placebo in Compensated Cirrhosis.	PHASE2	COMPLETED
Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis	PHASE2	COMPLETED
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab	PHASE1/PHASE2	RECRUITING
Radiation Therapy and Bortezomib and Cetuximab With or Without Cisplatin to Treat Head and Neck Cancer	PHASE1	COMPLETED
Itacitinib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
Effect of Different Therapeutic Strategies on Regulatory T Cells in Kidney Transplantation	nan	COMPLETED
Evaluation of the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients	nan	RECRUITING
Card14gene (rs34367357 ) Polymorphism in Egyptian Psoriatic and Psoriatic Arthritis Patient	nan	RECRUITING
Pituitary Derived-Intermedin is an Estrogen-Modulated Factor for Reducing Blood Pressure	nan	UNKNOWN
Pigeon Peas (Cajanus Cajan) : a Natural Anti-inflammatory Facilitating Weight Loss in Obese Patients Returning to Sport?	nan	UNKNOWN
Evaluation of Human Melanocytes After the Use of PRP Versus Fractional CO2 Laser in Vitiligo	nan	UNKNOWN
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients	nan	UNKNOWN
Effects of Mulberry Juice on Inflammatory Status and Clinical Symptoms in Patients With General Anxiety Disorder	nan	UNKNOWN
Androgenetic Alopecia and the JAK-STAT Pathway	nan	COMPLETED
Immune Interactions in Severe Asthma	nan	COMPLETED
Action of Essential Fatty Acids on the Expression of Antioxidant Genes and Athletic Performance	nan	COMPLETED
Comparison Of Efficacy Of Tazarotene 0.045% Vs Halobetasol Propionate 0.01% Lotion For Treatment of Scalp Psoriasis	nan	COMPLETED
The Effects of Omega-3 Status and Supplementation on Tendon Structure in Competitive Athletes	nan	UNKNOWN
Mitochondrial Function of Immune Cells in Sepsis	nan	COMPLETED
The Investigation on the Expression of High Mobility Group Protein Box-1 (HMGB1) in Peripheral Blood of Vitiligo Patients and Healthy Controls According to Clinical Features, Treatment and Disease Activity	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Adipocytokines in Endometrial Cancer	nan	COMPLETED
Insulin Iontophoresis Mixed With Oleic Acid Versus Topical Insulin in Patients With Chronic Diabetic Foot Ulcer	nan	UNKNOWN
Detection of Krupple Like Factor -1(KLF1/ EKLF) DNA Mutations in Beta Thalassemia Patients	nan	NOT_YET_RECRUITING
The Phosphodiesterase-3 Inhibitor Cilostazol as an Adjunctive to Antidepressants in Patients With Major Depressive Disorder.	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a JUN binder may also engage these)

Protein	Name	Similarity
P17325	—	1.000	P17325 →
O77627	—	1.000	O77627 →
P05627	—	1.000	P05627 →
P56432	—	1.000	P56432 →
P12981	—	1.000	P12981 →
P18870	—	1.000	P18870 →
P54864	—	1.000	P54864 →
P05411	—	0.998	P05411 →
P16951	—	0.992	P16951 →
A7YY54	—	0.990	A7YY54 →
P79703	—	0.989	P79703 →
O93602	—	0.988	O93602 →
P17275	—	0.987	P17275 →
P15336	—	0.986	P15336 →
Q8R0S1	—	0.986	Q8R0S1 →
Q00969	—	0.985	Q00969 →
P15066	—	0.985	P15066 →
P27921	—	0.983	P27921 →
P09450	—	0.983	P09450 →
P24898	—	0.983	P24898 →
Q0VBZ5	—	0.983	Q0VBZ5 →
Q02930	—	0.982	Q02930 →
Q5R9C9	—	0.981	Q5R9C9 →
JUND	Transcription factor JunD	0.981	landscape →
P17544	—	0.981	P17544 →
P52909	—	0.980	P52909 →
Q4VGL6	—	0.979	Q4VGL6 →
Q9UQB3	—	0.979	Q9UQB3 →
Q66IV1	—	0.979	Q66IV1 →
P47930	—	0.978	P47930 →