Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.51 |
| ▸ | HTR2B | P41595 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469000 | 0.89 | HTR2C (0.49) | HTR2CHTR2BHTR2A | |
| SCHEMBL25381760 | 0.79 | PDPK1 (0.40) | — | |
| SCHEMBL29960396 | 0.78 | HTR2C (0.45) | HTR2CHTR2BHTR2ATAAR1PNMT | |
| Hydrochloric Acid SCHEMBL29959813 | 0.77 | HTR2C (0.42) | HTR2CHTR2BHTR2ATAAR1PNMT | |
| SCHEMBL16353671 | 0.77 | HTR2C (0.47) | HTR2CHTR2BHTR2ATAAR1PNMT | |
| Hydrochloric Acid SCHEMBL29959957 | 0.76 | HTR2C (0.44) | HTR2CHTR2BHTR2ATAAR1PNMT | |
| Hydrochloric Acid SCHEMBL16353822 | 0.75 | HTR2C (0.46) | HTR2CHTR2BHTR2ATAAR1PNMT | |
| SCHEMBL29370750 | 0.74 | HTR2A (0.42) | HTR2ATAAR1 | |
| SCHEMBL16353840 | 0.74 | HTR2C (0.45) | HTR2CHTR2BHTR2ATAAR1PNMT | |
| SCHEMBL16353834 | 0.74 | HTR2C (0.45) | HTR2CHTR2BHTR2ATAAR1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957914-A | ANTIDEPRESSANTS, ANXIOLYTICS, HYPOTENSIVE AGENTS | SYNTEX (U.S.A.) INC. (US) | 1990-09-18 | — | — | US | disclosed |