SCHEMBL29960396

SCHEMBL29960396

c1cc2c3c(c1)COCC3CNCC2

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 10/20 0.45
HTR2A P28223 7/20 0.39
HTR2B P41595 5/20 0.39
TAAR1 Q96RJ0 1/20 0.36
PNMT P11086 2/20 0.35
CD44 P16070 1/20 0.35
MAOB P27338 1/20 0.35
PARP1 P09874 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29959957 0.98 HTR2C (0.44) HTR2CHTR2AHTR2BTAAR1PNMT
SCHEMBL10469682 0.78 HTR2C (0.51) HTR2CHTR2AHTR2BTAAR1PNMT
SCHEMBL16353840 0.77 HTR2C (0.45) HTR2CHTR2AHTR2BTAAR1PNMT
Hydrochloric Acid SCHEMBL29960295 0.77 HTR2C (0.39) HTR2CHTR2AHTR2BPNMT
Hydrochloric Acid SCHEMBL29960845 0.77 HTR2A (0.37) HTR2CHTR2AHTR2BPNMT
Hydrochloric Acid SCHEMBL16353757 0.76 HTR2C (0.44) HTR2CHTR2AHTR2BTAAR1PNMT
Hydrochloric Acid SCHEMBL29960859 0.76 HTR2C (0.48) HTR2CHTR2AHTR2BPNMT
Hydrochloric Acid SCHEMBL29961251 0.76 HTR2A (0.40) HTR2CHTR2AHTR2B
Hydrochloric Acid SCHEMBL29960531 0.76 HTR2A (0.39) HTR2CHTR2AHTR2BPNMT
Hydrochloric Acid SCHEMBL29960541 0.75 HTR2A (0.38) HTR2CHTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed