Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 18/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10470124 | 0.97 | PTAFR (0.74) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL10470033 | 0.92 | PTAFR (0.65) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL10469778 | 0.89 | PTAFR (0.63) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL10455817 | 0.89 | PTAFR (0.68) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL10471586 | 0.88 | OPRK1 (0.68) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| Apafant SCHEMBL29528926 | 0.86 | PTAFR (1.00) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| Apafant SCHEMBL94167 | 0.86 | PTAFR (1.00) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL10508820 | 0.86 | OPRK1 (0.67) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL9667907 | 0.85 | OPRK1 (0.66) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL10469901 | 0.85 | OPRK1 (0.66) | PTAFRCYP3A4ALOX15OPRK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900729-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1990-02-13 | — | — | US | disclosed |
| EP-0230942-A2 | Thieno-1,4-diazepines | BOEHRINGER INGELHEIM KG (DE) | 1987-08-05 | — | — | EP | disclosed |