Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 18/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471097 | 0.91 | TBXAS1 (0.63) | TBXAS1TBXA2RMEN1CYP1A2CYP3A4 | |
| SCHEMBL10471165 | 0.85 | TBXAS1 (0.60) | TBXAS1TBXA2RMEN1CYP1A2CYP3A4 | |
| SCHEMBL10471502 | 0.85 | TBXAS1 (0.75) | TBXAS1TBXA2RMEN1CYP1A2CYP3A4 | |
| SCHEMBL10471461 | 0.82 | CYP1A2 (0.61) | TBXAS1TBXA2RMEN1CYP1A2CYP3A4 | |
| SCHEMBL10401597 | 0.82 | TBXA2R (0.61) | TBXAS1TBXA2RMEN1CYP1A2CYP3A4 | |
| SCHEMBL10470720 | 0.81 | TBXA2R (0.60) | TBXAS1TBXA2RMEN1CYP1A2CYP3A4 | |
| SCHEMBL10471493 | 0.81 | TBXAS1 (0.57) | TBXAS1 | |
| SCHEMBL10471108 | 0.79 | TBXAS1 (0.80) | TBXAS1TBXA2RMEN1CYP1A2CYP3A4 | |
| SCHEMBL10647339 | 0.78 | CYP1A2 (0.62) | TBXAS1TBXA2RMEN1CYP1A2CYP3A4 | |
| SCHEMBL10471604 | 0.78 | TBXAS1 (0.54) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921866-A | 1,3-dioxanes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-01 | — | — | US | disclosed |
| EP-0288279-A2 | 1,3-Dioxanes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-26 | — | — | EP | disclosed |