Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469568 | 0.96 | ALDH1A1 (0.58) | RAB9AALDH1A1KDM4ECYP2C9CYP1A2 | |
| SCHEMBL31390541 | 0.94 | ALDH1A1 (0.63) | RAB9AALDH1A1KDM4ECYP2C9CYP1A2 | |
| SCHEMBL1433337 | 0.94 | ALDH1A1 (0.63) | RAB9AALDH1A1KDM4ECYP2C9CYP1A2 | |
| SCHEMBL10467928 | 0.91 | ALDH1A1 (0.53) | RAB9AALDH1A1KDM4ECYP2C9CYP1A2 | |
| SCHEMBL10469524 | 0.90 | HPGD (0.61) | RAB9AALDH1A1KDM4ECYP2C9CYP1A2 | |
| SCHEMBL10469507 | 0.90 | ALDH1A1 (0.56) | RAB9AALDH1A1KDM4ECYP2C9CYP1A2 | |
| SCHEMBL10469211 | 0.89 | ALDH1A1 (0.55) | RAB9AALDH1A1KDM4ECYP2C9CYP1A2 | |
| SCHEMBL10468212 | 0.89 | ALDH1A1 (0.53) | RAB9AALDH1A1KDM4ECYP2C9CYP1A2 | |
| SCHEMBL10470174 | 0.88 | KMT2A (0.68) | RAB9AALDH1A1KDM4ECYP2C9CYP1A2 | |
| SCHEMBL10469519 | 0.88 | ALDH1A1 (0.56) | RAB9AALDH1A1KDM4ECYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952574-A | Antiarrhythmic substituted N-(2-piperidylmethyl)benzamides | RIKER LABORATORIES, INC. (US) | 1990-08-28 | — | — | US | disclosed |