Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10470595 | 1.00 | ALOX5 (0.59) | ALOX5NR1H4MAOBNPC1RAB9A | |
| SCHEMBL10470438 | 0.85 | NPC1 (0.59) | ALOX5NR1H4MAOBNPC1RAB9A | |
| SCHEMBL10470436 | 0.85 | NPC1 (0.59) | ALOX5NR1H4MAOBNPC1RAB9A | |
| SCHEMBL10471722 | 0.84 | ALOX5 (0.58) | ALOX5NR1H4MAOBNPC1RAB9A | |
| SCHEMBL10471721 | 0.84 | ALOX5 (0.58) | ALOX5NR1H4MAOBNPC1RAB9A | |
| SCHEMBL10472221 | 0.82 | ALOX5 (0.54) | ALOX5NR1H4MAOBNPC1RAB9A | |
| SCHEMBL10472220 | 0.82 | ALOX5 (0.54) | ALOX5NR1H4MAOBNPC1RAB9A | |
| SCHEMBL10483609 | 0.81 | ALOX5 (0.56) | ALOX5MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10471770 | 0.81 | ALOX5 (0.56) | ALOX5MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10471769 | 0.81 | ALOX5 (0.56) | ALOX5MAOBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975455-A | ANTITUMOR, ANTICARCINOGENIC AGENT; SKIN DISORDERS | ADIR ET CIE (FR) | 1990-12-04 | — | — | US | disclosed |