SCHEMBL10472158

SCHEMBL10472158

C=C(c1ccc(N(C)c2ccc(C)cc2)cc1)c1ccc(N(C)c2ccc(C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 10/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 5/20 0.41
MAPT P10636 5/20 0.41
HSD17B10 Q99714 2/20 0.41
GFER P55789 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
LMNA P02545 3/20 0.39
CES1 P23141 2/20 0.39
CES2 O00748 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 2/20 0.38
HPGD P15428 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
NPC1 O15118 1/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10692801 0.94 MEN1 (0.63) MEN1KMT2AALDH1A1TSHRHTT
SCHEMBL9099853 0.87 MEN1 (0.70) MEN1KMT2AALDH1A1TSHRHTT
SCHEMBL9554883 0.84 MEN1 (0.50) MEN1KMT2AALDH1A1TSHRHTT
SCHEMBL19583387 0.84 MEN1 (0.50) MEN1KMT2AALDH1A1TSHRHTT
SCHEMBL893597 0.83 HTT (0.55) MEN1KMT2AALDH1A1HTTMAPT
SCHEMBL4412916 0.83 HTT (0.55) MEN1KMT2AALDH1A1HTTMAPT
SCHEMBL10473987 0.83 MEN1 (0.70) MEN1KMT2AALDH1A1HTTMAPT
SCHEMBL517128 0.81 ALDH1A1 (0.67) ALDH1A1TSHRMAPTHSD17B10GFER
SCHEMBL22083898 0.81 ALDH1A1 (0.67) ALDH1A1TSHRMAPTHSD17B10GFER
SCHEMBL15854781 0.81 ALDH1A1 (0.67) ALDH1A1TSHRMAPTHSD17B10GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4898941-A Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-02-06 US disclosed
US-4770973-A READABLE BY OPTICAL DEVICES AND FIXED BY LIGHT Kanzaki Paper Manufacturing Limited (JP) 1988-09-13 US disclosed
US-4748148-A Recording system utilizing phthalide derivatives as colorless chromogenic material NEW OJI PAPER CO., LTD. (JP) 1988-05-31 US disclosed
EP-0257591-A2 Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-03-02 EP disclosed
US-4641160-A Recording system utilizing phthalide derivatives as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-02-03 US disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed