Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823228 | 0.98 | HPGD (0.40) | HPGDLMNAALDH1A1MAPTHTT | |
| SCHEMBL10472439 | 0.97 | HPGD (0.39) | HPGDLMNAALDH1A1MAPTHTT | |
| SCHEMBL3675507 | 0.81 | MEN1 (0.55) | HPGDLMNAALDH1A1MAPTGABRA1 | |
| SCHEMBL3680287 | 0.81 | CES2 (0.47) | LMNAALDH1A1MAPTHTTRAB9A | |
| SCHEMBL3680288 | 0.81 | CES2 (0.47) | LMNAALDH1A1MAPTHTTRAB9A | |
| SCHEMBL3675506 | 0.81 | MEN1 (0.55) | HPGDLMNAALDH1A1MAPTGABRA1 | |
| SCHEMBL3436492 | 0.81 | MEN1 (0.55) | HPGDLMNAALDH1A1MAPTGABRA1 | |
| SCHEMBL3680333 | 0.77 | CES2 (0.47) | LMNAALDH1A1MAPTHTT | |
| SCHEMBL3680330 | 0.77 | CES2 (0.47) | LMNAALDH1A1MAPTHTT | |
| SCHEMBL10472622 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950777-A | Herbicidally active derivatives of N-phenyl-3,4,5,6-tetrahydrophthalimide | CIBA-GEIGY CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |
| US-4824476-A | PLANT GROWTH REGULATOR | CIBA-GEIGY CORPORATION (US) | 1989-04-25 | — | — | US | disclosed |