Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473931 | 1.00 | MAPT (0.51) | MAPTCYP1A2CYP3A4CYP2C19GFER | |
| SCHEMBL10473874 | 0.98 | MAPT (0.53) | MAPTCYP1A2CYP3A4CYP2C19GFER | |
| SCHEMBL10473036 | 0.93 | MAPT (0.54) | MAPTCYP1A2CYP3A4CYP2C19GFER | |
| SCHEMBL10471654 | 0.92 | MAPT (0.55) | MAPTCYP1A2CYP3A4CYP2C19GFER | |
| SCHEMBL10474521 | 0.91 | ALDH1A1 (0.51) | MAPTGFERSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10471707 | 0.90 | MAPT (0.43) | MAPTCYP1A2CYP3A4CYP2C19GFER | |
| SCHEMBL10473899 | 0.90 | SMN1; SMN2 (0.44) | MAPTCYP1A2CYP3A4CYP2C19GFER | |
| SCHEMBL10471787 | 0.90 | MAPT (0.43) | MAPTCYP1A2CYP3A4CYP2C19GFER | |
| SCHEMBL10473308 | 0.88 | ALDH1A1 (0.58) | MAPTGFERSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL10471442 | 0.88 | MAPT (0.44) | MAPTCYP1A2CYP3A4CYP2C19GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898941-A | Process for preparing diphenylalkene derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0257591-A2 | Process for preparing diphenylalkene derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |