SCHEMBL1047299

SCHEMBL1047299

OCCCCCCCCO[Al](OCCCCCCCCO)OCCCCCCCCO

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 1/20 0.36
GAA P10253 1/20 0.34
ACHE P22303 6/20 0.32
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29226129 0.88 TSHR (0.32) MEN1KMT2AALDH1A1TSHR
SCHEMBL29876479 0.79
SCHEMBL27689255 0.79 LMNA (0.38) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL29876485 0.79
SCHEMBL29876791 0.75
SCHEMBL28889963 0.74 TSHR (0.44) MEN1KMT2AALDH1A1TSHR
SCHEMBL8936938 0.71 MEN1 (0.55) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL6047745 0.71 MEN1 (0.55) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL9011790 0.71 MEN1 (0.55) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL225132 0.71 MEN1 (0.42) LMNAMEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8563675-B2 Curable compositions composed of silanes with two hydrolyzable groups HENKEL AG & CO. KGAA (DE) 2013-10-22 US disclosed
EP-2178963-B1 SILANE-CROSSLINKING ADHESIVE OR SEALANT COMPRISING N-SILYLALKYLAMIDES AND USE THEREOF HENKEL AG & CO KGAA (DE) 2013-07-17 EP disclosed
US-8450411-B2 Curable composition having a silane-modified reactive thinner HENKEL AG & CO. KGAA (DE) 2013-05-28 US disclosed
EP-2076568-B1 COMPOSITIONS CONSISTING OF PARTIALLY SILYL-TERMINATED POLYMERS HENKEL AG & CO KGAA (DE) 2012-05-23 EP disclosed
EP-2449033-A2 CURABLE COMPOSITION HAVING A SILANE-MODIFIED REACTIVE THINNER Henkel AG & Co. KGaA (DE) 2012-05-09 EP disclosed
US-20120108730-A1 CURABLE COMPOSITION HAVING A SILANE-MODIFIED REACTIVE THINNER HENKEL AG & CO. KGAA (DE) 2012-05-03 US disclosed
US-8067508-B2 Compositions consisting of partially silyl-terminated polymers HENKEL AG & CO. KGAA (DE) 2011-11-29 US disclosed
EP-2176315-B1 CURABLE COMPOSITIONS COMPOSED OF SILANES WITH TWO HYDROLYZABLE GROUPS HENKEL AG & CO KGAA (DE) 2011-03-30 EP disclosed
WO-2011000843-A2 CURABLE COMPOSITION HAVING A SILANE-MODIFIED REACTIVE THINNER HENKEL AG & CO. KGAA (DE) 2011-01-06 WO disclosed
US-20100204387-A1 CURABLE COMPOSITIONS COMPOSED OF SILANES WITH TWO HYDROLYZABLE GROUPS HENKEL AG & CO. KGAA (DE) 2010-08-12 US disclosed
US-20100143712-A1 SILANE-CROSSLINKING ADHESIVE OR SEALANT COMPRISING N-SILYLALKYLAMIDES AND USE THEREOF HENKEL AG & CO. KGAA (DE) 2010-06-10 US disclosed
EP-2178963-A1 SILANE-CROSSLINKING ADHESIVE OR SEALANT COMPRISING N-SILYLALKYLAMIDES AND USE THEREOF Henkel AG & Co. KGaA (DE) 2010-04-28 EP disclosed
EP-2176315-A1 CURABLE COMPOSITIONS COMPOSED OF SILANES WITH TWO HYDROLYZABLE GROUPS Henkel AG & Co. KGaA (DE) 2010-04-21 EP disclosed
US-20100081757-A1 COMPOSITIONS CONSISTING OF PARTIALLY SILYL-TERMINATED POLYMERS HENKEL AG & CO. KGAA (DE) 2010-04-01 US disclosed
WO-2010004038-A1 CURABLE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2010-01-14 WO disclosed
EP-2076568-A2 COMPOSITIONS CONSISTING OF PARTIALLY SILYL-TERMINATED POLYMERS Henkel AG & Co. KGaA (DE) 2009-07-08 EP disclosed
WO-2009021928-A1 CURABLE COMPOSITIONS COMPOSED OF SILANES WITH TWO HYDROLYZABLE GROUPS HENKEL AG & CO. KGAA (DE) 2009-02-19 WO disclosed
WO-2009022012-A1 SILANE-CROSSLINKING ADHESIVE OR SEALANT COMPRISING N-SILYLALKYLAMIDES AND USE THEREOF HENKEL AG & CO. KGAA (DE) 2009-02-19 WO disclosed
WO-2008043735-A2 COMPOSITIONS CONSISTING OF PARTIALLY SILYL-TERMINATED POLYMERS HENKEL AG & CO. KGAA (DE) 2008-04-17 WO disclosed