Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 5/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385739 | 0.94 | KCNH2 (0.55) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10472674 | 0.92 | KCNH2 (0.57) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10472075 | 0.91 | KCNH2 (0.56) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10472818 | 0.87 | KCNH2 (0.59) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL12819447 | 0.86 | TOP2A (0.52) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10472204 | 0.83 | KCNH2 (0.68) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10555158 | 0.82 | KDM4E (0.56) | KCNH2ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL8112091 | 0.81 | KCNH2 (0.58) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL12836936 | 0.79 | KCNH2 (0.61) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10572786 | 0.79 | KCNH2 (0.79) | KCNH2ALDH1A1POLBOPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935420-A | MICROBIOCIDES, ANTISEPTICS | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-06-19 | — | — | US | disclosed |