Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10514378 | 0.89 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL8385739 | 0.86 | KCNH2 (0.55) | KDM4EHSD17B10ALDH1A1HPGDAADAT | |
| SCHEMBL10473512 | 0.82 | KCNH2 (0.61) | KDM4EHSD17B10ALDH1A1HPGDAADAT | |
| SCHEMBL311638 | 0.81 | KDM4E (0.67) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL9749343 | 0.79 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL12819447 | 0.78 | TOP2A (0.52) | KDM4EHSD17B10ALDH1A1HPGDAADAT | |
| Hydrochloric Acid SCHEMBL10511578 | 0.78 | KDM4E (0.66) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| Hydrochloric Acid SCHEMBL9151911 | 0.77 | KDM4E (0.66) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL9749919 | 0.77 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL9142993 | 0.77 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1HPGDPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889857-A | BACTERICIDES; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-12-26 | — | — | US | disclosed |