SCHEMBL10474178

SCHEMBL10474178

COC(=O)C(C)Oc1ccc(Oc2ncc(Cl)cc2N)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.57
MAPT P10636 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
LMNA P02545 2/20 0.43
APEX1 P27695 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43
PTGER4 P35408 3/20 0.43
MAPK1 P28482 1/20 0.42
LIPE Q05469 3/20 0.42
MAP4K4 O95819 2/20 0.42
BCHE P06276 1/20 0.41
PTGER2 P43116 1/20 0.41
TP53 P04637 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
NFKB1 P19838 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9168919 0.88 MAP4K4 (0.54) L3MBTL1MAPTMEN1KMT2ALMNA
SCHEMBL9450065 0.88 L3MBTL1 (0.71) L3MBTL1MAPTMEN1KMT2ALMNA
SCHEMBL8683764 0.87 L3MBTL1 (0.58) L3MBTL1MAPTMEN1KMT2ALMNA
SCHEMBL9215075 0.86 L3MBTL1 (0.57) L3MBTL1MAPTMEN1KMT2ALMNA
SCHEMBL10474119 0.86 L3MBTL1 (0.57) L3MBTL1MAPTMEN1KMT2ALMNA
SCHEMBL10745519 0.85 L3MBTL1 (0.52) L3MBTL1MAPTMEN1KMT2ALMNA
SCHEMBL11558716 0.83 L3MBTL1 (0.54) L3MBTL1MAPTMEN1KMT2ALMNA
SCHEMBL10475397 0.82 MAPT (0.53) L3MBTL1MAPTMEN1KMT2ALMNA
SCHEMBL9792113 0.82 L3MBTL1 (0.53) L3MBTL1MAPTMEN1KMT2ALMNA
SCHEMBL9792030 0.82 L3MBTL1 (0.53) L3MBTL1MAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4935051-A POSTEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1990-06-19 US disclosed
EP-0148119-B1 AMIDES OF 2-PHENOXYPROPIONIC ACID CIBA-GEIGY AG (CH) 1989-05-03 EP disclosed
EP-0305593-A2 Intermediates for cyanamides of 2-pyridinyloxyphenoxypropionic acid CIBA-GEIGY AG (CH) 1989-03-08 EP disclosed
US-4759796-A Used together with a carrier and other adjuvant CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
US-4640703-A CONTROLLING GRASSES IN CROPS CIBA-GEIGY CORPORATION (US) 1987-02-03 US disclosed
EP-0148119-A2 Amides of 2-phenoxypropionic acid CIBA-GEIGY AG (CH) 1985-07-10 EP disclosed