Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminosalicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.96 |
| ▸ | MAPT | P10636 | 5/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.96 |
| ▸ | GAA | P10253 | 2/20 | 0.96 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.96 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.96 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | KDR | P35968 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | TNF | P01375 | 1/20 | 0.67 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminosalicylic Acid SCHEMBL871847 | 1.00 | ALDH1A1 (0.96) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL6400626 | 0.98 | ALDH1A1 (0.92) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL6400637 | 0.98 | ALDH1A1 (0.92) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL3333393 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL2262 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL30337954 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL29450213 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL564092 | 0.96 | ALDH1A1 (0.96) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL11788850 | 0.96 | ALDH1A1 (0.96) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL29030136 | 0.96 | ALDH1A1 (0.96) | ALDH1A1KDM4EMAPTCYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116916477-B | Amorphous heat superconducting heating belt and preparation method thereof | 唐山非晶科技有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-116916477-A | Amorphous heat superconducting heating belt and preparation method thereof | 唐山非晶科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-101801414-B | Oral and skin compositions | NIHON KODOIRYO KENKYUKAI CO LT | 2013-04-03 | — | — | CN | claimed |
| CN-101801414-A | The oral cavity is used and skin composition | NIHON KODOIRYO KENKYUKAI CO LT | 2010-08-11 | — | — | CN | claimed |
| US-20100080847-A1 | MEDICINAL COMPOSITIONS QUICKLY DISINTEGRATING IN THE ORAL CAVITY AND PROCESS FOR PRODUCING THE SAME | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-04-01 | — | — | US | claimed |
| CN-1596120-A | Pharmaceutical composition for transnasal absorption | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-03-16 | — | — | CN | claimed |
| US-20040014680-A1 | Medicinal compositions quickly disintegrating in the oral cavity and process for producing the same | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-01-22 | — | — | US | claimed |
| CN-1469737-A | Medicinal composition capable of rapidly disintegrating in oral cavity and preparation method thereof | ��һ��������ҩ��ʽ���� | 2004-01-21 | — | — | CN | claimed |
| EP-1334716-A1 | MEDICINAL COMPOSITIONS QUICKLY DISINTEGRATING IN THE ORAL CAVITY AND PROCESS FOR PRODUCING THE SAME | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-08-13 | — | — | EP | claimed |
| CN-1406124-A | Nasal administration of cyclic peptide compositions | BASILEA PHARMACUEITCA AG (CH) | 2003-03-26 | — | — | CN | claimed |
| CN-1076624-C | Nasally administrable compositions | DOTT CO LTD (JP) | 2001-12-26 | — | — | CN | claimed |
| EP-0681833-B1 | Nasally administrable compositions | DOTT RES LAB (JP) | 2001-06-13 | — | — | EP | claimed |
| EP-0943336-A1 | PEPTIDE-CONTAINING PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION | DOTT RESEARCH LABORATORY (JP) | 1999-09-22 | — | — | EP | claimed |
| CN-1228708-A | Peptide-containing drug compositions for oral administration | DOTT CO LTD (JP) | 1999-09-15 | — | — | CN | claimed |
| CN-1117874-A | Nasally administrable compositions | DOTT RESEARCH LAB (JP) | 1996-03-06 | — | — | CN | claimed |
| US-5288503-A | WATER-PERMEABLE DIFFUSION BARRIER OF POLYVINYL ALCOHOL | SRCHEM INCORPORATED (US) | 1994-02-22 | — | — | US | claimed |
| US-5260066-A | Cryogel bandage containing therapeutic agent | SRCHEM INCORPORATED (US) | 1993-11-09 | — | — | US | claimed |
| EP-4681776-A2 | ANTIMICROBIAL THERAPY | The Regents of the University of California (US) | 2026-01-21 | — | — | EP | disclosed |
| EP-0253901-A1 | SUSTAINED-RELEASE PREPARATION | TEIJIN LIMITED (JP) | 1988-01-27 | — | — | EP | disclosed |
| EP-0227836-A1 | SUSTAINED RELEASING PATCH | TEIJIN LIMITED (JP) | 1987-07-08 | — | — | EP | disclosed |