Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD1 | P21728 | 5/20 | 0.38 |
| ▸ | DRD4 | P21917 | 5/20 | 0.38 |
| ▸ | DRD5 | P21918 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357033 | 0.90 | EPHX1 (0.47) | EPHX1ALDH1A1GBA1EBPSIGMAR1 | |
| Hydrochloric Acid SCHEMBL27889721 | 0.88 | EPHX1 (0.46) | EPHX1ALDH1A1GBA1SIGMAR1DRD2 | |
| SCHEMBL8283682 | 0.85 | SIGMAR1 (0.42) | EPHX1GBA1SIGMAR1HTR1ADRD2 | |
| SCHEMBL2357921 | 0.85 | EPHX1 (0.52) | EPHX1ALDH1A1EBPSIGMAR1DRD4 | |
| Tetrahydrofuran SCHEMBL27678687 | 0.83 | EPHX1 (0.41) | EPHX1ALDH1A1BCHEDRD3 | |
| SCHEMBL7324183 | 0.83 | GBA1 (0.43) | GBA1GUSBEBPSIGMAR1BCHE | |
| SCHEMBL9936176 | 0.83 | EPHX1 (0.44) | EPHX1ALDH1A1GBA1EBPSIGMAR1 | |
| SCHEMBL27419278 | 0.82 | EPHX1 (0.44) | EPHX1ALDH1A1GUSBEBPSIGMAR1 | |
| SCHEMBL5659819 | 0.82 | EBP (0.47) | EPHX1GUSBEBPSIGMAR1BCHE | |
| SCHEMBL10682538 | 0.82 | EPHX1 (0.56) | EPHX1ALDH1A1EBPSIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4894221-A | Method of treating plaque using morpholine compounds | AB FERROSAN (SE) | 1990-01-16 | — | — | US | disclosed |
| US-4636382-A | ANTIPLAQUE | AB FERROSAN (SE) | 1987-01-13 | — | — | US | disclosed |
| EP-0038785-B1 | NOVEL MORPHOLINO COUMPOUNDS | AB Ferrosan (SE) | 1985-11-13 | — | — | EP | disclosed |
| EP-0038785-A1 | Novel morpholino coumpounds | AB Ferrosan (SE) | 1981-10-28 | — | — | EP | disclosed |