Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693008 | 0.88 | ALDH1A1 (0.33) | ALDH1A1MAPK1SMN1; SMN2KDM4ERECQL | |
| SCHEMBL9201226 | 0.81 | — | — | |
| SCHEMBL27693275 | 0.81 | — | — | |
| SCHEMBL10561410 | 0.80 | MEN1 (0.33) | MAPK1KDM4EMEN1KMT2A | |
| SCHEMBL27693019 | 0.79 | KDM4E (0.31) | KDM4EMEN1KMT2A | |
| SCHEMBL27693031 | 0.79 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL27674760 | 0.78 | — | — | |
| SCHEMBL27693011 | 0.78 | DHODH (0.32) | — | |
| SCHEMBL10674285 | 0.77 | MAPT (0.32) | — | |
| SCHEMBL10371771 | 0.76 | ALDH1A1 (0.34) | ALDH1A1MAPK1SMN1; SMN2KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921530-A | Certain 3,5-pyridine dicarboxylates, their thio analogues having herbicidal activity | MONSANTO COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4835279-A | 2,6-substituted pyridine compounds | MONSANTO COMPANY (US) | 1989-05-30 | — | — | US | disclosed |