SCHEMBL1047482

SCHEMBL1047482

CC(C)COC(C)OC(=O)C(N)C1(CC(=O)O)CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
BLM P54132 1/20 0.33
CACNA2D1 P54289 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3398321 0.86 USP2 (0.37) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL1563267 0.86 USP2 (0.37) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL3182386 0.84 SMN1; SMN2 (0.35) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL4754466 0.82 USP2 (0.33) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL4756188 0.82 USP2 (0.33) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL4757195 0.80 CYP1A2 (0.32) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL6885636 0.78 USP2 (0.35) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL5147427 0.78 USP2 (0.35) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL27622480 0.77 GABRP (0.38) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL5313513 0.77 USP2 (0.34) USP2ALDH1A1LMNACYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2275401-B1 Crystalline 1-{[(alpha-isobutanoyloxyethoxy)carbonyl]aminomethyl}-1-cyclohexane acetic acid XENOPORT INC (US) 2013-04-03 EP disclosed
EP-2275401-A1 Crystalline 1-{[(a-isobutanoyloxyethoxy)carbonyl]aminomethyl}-1-cyclohexane acetic acid XenoPort, Inc. (US) 2011-01-19 EP disclosed