Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 2/20 | 0.58 |
| ▸ | ADCY5 | O95622 | 8/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | PDE8B | O95263 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | NPM1 | P06748 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138477 | 0.93 | AHCY (0.56) | AHCYADCY5ADORA2AADORA3ADORA2B | |
| SCHEMBL10475401 | 0.86 | AHCY (0.42) | AHCYADCY5ADORA2AADORA3ADORA2B | |
| SCHEMBL24686947 | 0.83 | ADORA2A (0.54) | AHCYADCY5ADORA2AADORA3ADORA2B | |
| SCHEMBL21138474 | 0.82 | AHCY (0.48) | AHCYADCY5ADORA2AADORA3ADORA2B | |
| SCHEMBL10475250 | 0.81 | AHCY (0.37) | AHCYADCY5PDE8B | |
| SCHEMBL21138755 | 0.80 | AHCY (0.47) | AHCYADCY5ADORA2AADORA3ADORA2B | |
| SCHEMBL21138855 | 0.80 | AHCY (0.47) | AHCYADCY5ADORA2AADORA3ADORA2B | |
| SCHEMBL10474172 | 0.78 | ADCY5 (0.74) | AHCYADCY5ADORA2AADORA3ADORA2B | |
| SCHEMBL21138851 | 0.78 | ADORA2A (0.56) | AHCYADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL21057392 | 0.77 | AHCY (0.48) | AHCYADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916224-A | VIRICIDES FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1990-04-10 | — | — | US | disclosed |