Triphosphate

SCHEMBL10475692

Cc1cn(C(OCCO)c2ccco2)c(=O)[nH]c1=O.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	TYMP	P19971	4/20	0.39

▸	POLB	P06746	3/20	0.36

▸	POLA1	P09884	1/20	0.36

▸	POLD1	P28340	1/20	0.36

▸	MAPK1	P28482	1/20	0.35

▸	TK1	P04183	4/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

▸	LMNA	P02545	1/20	0.34

▸	ALB	P02768	1/20	0.34

▸	ADRA1A	P35348	1/20	0.34

▸	BLM	P54132	1/20	0.34

▸	HPGD	P15428	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10474575	0.91	MAPK1 (0.41)	TYMPPOLBMAPK1TK1ALDH1A1
Triphosphate SCHEMBL10475689	0.85	TYMP (0.40)	TYMPPOLBPOLA1POLD1MAPK1
Triphosphate SCHEMBL10474748	0.84	TYMP (0.38)	TYMPPOLBPOLA1POLD1TK1
Triphosphate SCHEMBL10475441	0.80	TYMP (0.46)	TYMPPOLBPOLA1POLD1TK1
Triphosphate SCHEMBL10475447	0.79	TYMP (0.43)	TYMPPOLBPOLA1POLD1TK1
SCHEMBL10475696	0.74	HPGD (0.46)	TYMPMAPK1TK1HPGD
SCHEMBL10474543	0.73	TYMP (0.37)	TYMPPOLBMAPK1TK1ALDH1A1
SCHEMBL10474541	0.71	TK2 (0.39)	TYMPPOLBMAPK1TK1ALDH1A1
SCHEMBL10474750	0.70	TK1 (0.40)	TYMPMAPK1TK1ALDH1A1HPGD
SCHEMBL10474805	0.69	TK1 (0.36)	TYMPMAPK1TK1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1990009999-A1	SECO-NUCLEOSIDE DERIVATIVES AND DRUGS CONTAINING THEM	BOEHRINGER MANNHEIM GMBH (DE)	1990-09-07	—	—	WO	disclosed