Sugi Predict
/ Targets
/ TK1
Top predicted compounds (top 20 by supporting neighbours, then confidence)
Clinical trials — most relevant to TK1 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) |
PHASE3 | WITHDRAWN |
| Acelarin First Line Randomised Pancreatic Study |
PHASE2/PHASE3 | SUSPENDED |
| HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer |
PHASE1/PHASE2 | RECRUITING |
| Safety, Tolerance, Pharmacokinetic and Antiviral Study of Amdoxovir in Combination With Zidovudine in Adults With HIV |
PHASE1/PHASE2 | COMPLETED |
| Irinotecan and Capecitabine as Second-line Treatment for Advanced/Metastatic Biliary Tract Cancers |
PHASE2 | WITHDRAWN |
| Clofarabine Plus Cytarabine in Patients With Previously Untreated Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome |
PHASE2 | COMPLETED |
| A Phase II Study of Capecitabine and Docetaxel in Previously Untreated Advanced Non-Small Cell Lung Cancer Patients |
PHASE2 | COMPLETED |
| S0713: Oxaliplatin, Capecitabine, Cetuximab, and RT Followed By Surgery in Pts W/Stage II or III Rectal Cancer |
PHASE2 | COMPLETED |
| Docetaxel Versus Docetaxel Plus Cisplatin Versus Docetaxel Plus S-1 as Second-line Chemotherapy in Metastatic Gastric Cancer |
PHASE2 | UNKNOWN |
| A Phase II Study of TX Regimen as First-line Treatment for Asian Elderly Patients With Advanced Adenocarcinoma of Lung |
PHASE2 | COMPLETED |
| Prospective Phase II Randomized Trial of Postoperative Adjuvant Chemotherapy in Patients With High Risk Colon Cancer |
PHASE2 | UNKNOWN |
| Oncolytic Adenovirus-Mediated Gene Therapy for Lung Cancer |
PHASE1 | WITHDRAWN |
| FAU in Treating Patients With Advanced Solid Tumors or Lymphoma |
PHASE1 | COMPLETED |
| Gene Therapy for the Treatment of Brain Tumors |
PHASE1 | COMPLETED |
| Safety, Tolerability and Pharmacokinetics of Benfo-Oxythiamine (B-OT) in Healthy Volunteers |
PHASE1 | COMPLETED |
| AdV-tk Therapy With Surgery and Chemoradiation for Pancreas Cancer (PaTK01) |
PHASE1 | COMPLETED |
| A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors |
PHASE1 | COMPLETED |
| Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma |
PHASE1 | UNKNOWN |
| Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors |
PHASE1 | COMPLETED |
| Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors |
PHASE1 | COMPLETED |
| 3'-Deoxy-3'-[18F] Fluorothymidine and Fludeoxyglucose F 18 PET Scans in Evaluating Response to Cetuximab, Cisplatin, and Radiation Therapy in Patients With Advanced Cancer of the Oropharynx, Larynx, or Hypopharynx |
EARLY_PHASE1 | COMPLETED |
| Evaluation of Thymidine Kinase Activity in the Serum of Patients With Solid Tumors |
nan | UNKNOWN |
| Thymidine Kinase 1 in Risk Assessment for Hereditary Breast /Ovarian Cancer |
nan | UNKNOWN |
| Targeted Radiotherapy for Recurrent Prostate Cancer |
nan | UNKNOWN |
| Early Response Assessment of Induction Chemotherapy in Acute Myeloid Leukemia Patients Using F-18 FLT PET/CT |
nan | COMPLETED |
| Positron Emission Tomography Using 3'-Deoxy-3'-(18F) Fluorothymidine in Treating Women With Locally Advanced Cancer in One Breast Who Are Receiving Chemotherapy |
nan | COMPLETED |
| Correlation Between EGFR Mutation Using cfDNAs and Circulating Tumor Cells in Patients With NSCLC |
nan | UNKNOWN |
| 124I-FIAU Imaging in EBV and KSHV Associated Cancers |
nan | COMPLETED |
| [18F]FLT-PET as a Predictive Imaging Biomaker of Treatment Responses to Regorafenib |
nan | COMPLETED |
| A Phase I Trial of AVN944, an IMPDH Inhibitor, in Adults With Advanced Stage Solid Tumors |
nan | WITHDRAWN |
Related proteins — ESM-2 sequence neighbours (a TK1 binder may also engage these)