Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | PDE6D | O43924 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476296 | 1.00 | CNR2 (0.43) | CNR2SMYD3MCHR1P2RX7PPARG | |
| SCHEMBL10476261 | 1.00 | CNR2 (0.43) | CNR2SMYD3MCHR1P2RX7PPARG | |
| Succinic Acid SCHEMBL507022 | 0.96 | CNR2 (0.41) | CNR2SMYD3MCHR1P2RX7PPARG | |
| Succinic Acid SCHEMBL507228 | 0.96 | CNR2 (0.41) | CNR2SMYD3MCHR1P2RX7PPARG | |
| SCHEMBL10274759 | 0.86 | RXFP1 (0.44) | PDE6D | |
| SCHEMBL10476151 | 0.83 | HDAC6 (0.42) | SMYD3P2RX7MAPK14 | |
| Succinic Acid SCHEMBL507841 | 0.82 | RXFP1 (0.43) | PDE6D | |
| Hydrochloric Acid SCHEMBL2369279 | 0.82 | HDAC6 (0.41) | SMYD3P2RX7MAPK14 | |
| SCHEMBL10476175 | 0.82 | ALDH1A1 (0.41) | MCHR1 | |
| SCHEMBL10476173 | 0.82 | ALDH1A1 (0.41) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580780-B2 | 6 substituted 2, 3,4,5 tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonist | ELI LILLY AND COMPANY (US) | 2013-11-12 | — | — | US | claimed |
| EP-2479168-A1 | 6-Substituted 2,3,4,5-Tetrahydro-1H-Benzo [d]Azepines as 5-HT2C Receptor Agonists | ELI LILLY AND COMPANY (US) | 2012-07-25 | — | — | EP | claimed |