Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 11/20 | 0.43 |
| ▸ | HTR2C | P28335 | 10/20 | 0.43 |
| ▸ | HTR2A | P28223 | 9/20 | 0.43 |
| ▸ | PNMT | P11086 | 4/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL507113 | 0.99 | HTR2B (0.42) | HTR2BHTR2CHTR2APNMTADRA2A | |
| SCHEMBL10228824 | 0.86 | HTR2C (0.43) | HTR2BHTR2CHTR2APNMTADRA2A | |
| SCHEMBL10274751 | 0.86 | GBA1 (0.31) | — | |
| SCHEMBL10476292 | 0.84 | HTR2C (0.43) | HTR2BHTR2CHTR2APNMTADRA2A | |
| Hydrochloric Acid SCHEMBL507161 | 0.83 | HTR2C (0.42) | HTR2BHTR2CHTR2APNMTADRA2A | |
| SCHEMBL11947388 | 0.82 | HTR2C (0.39) | HTR2BHTR2CHTR2APNMTADRA2A | |
| SCHEMBL10228891 | 0.81 | CHRNB2 (0.39) | HTR2BHTR2CHTR2APNMTADRA2A | |
| SCHEMBL10228883 | 0.81 | HTR2B (0.39) | HTR2BHTR2CHTR2APNMTADRA2A | |
| SCHEMBL10228880 | 0.81 | HTR2C (0.39) | HTR2BHTR2CHTR2APNMTADRA2A | |
| SCHEMBL10228811 | 0.81 | HTR2C (0.44) | HTR2BHTR2CHTR2APNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580780-B2 | 6 substituted 2, 3,4,5 tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonist | ELI LILLY AND COMPANY (US) | 2013-11-12 | — | — | US | claimed |
| EP-2479168-A1 | 6-Substituted 2,3,4,5-Tetrahydro-1H-Benzo [d]Azepines as 5-HT2C Receptor Agonists | ELI LILLY AND COMPANY (US) | 2012-07-25 | — | — | EP | claimed |