Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.75 |
| ▸ | MEN1 | O00255 | 11/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.75 |
| ▸ | RAB9A | P51151 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | HTT | P42858 | 4/20 | 0.73 |
| ▸ | USP2 | O75604 | 4/20 | 0.73 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594463 | 0.82 | MEN1 (0.67) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL10476368 | 0.77 | MEN1 (0.52) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL10476376 | 0.75 | MEN1 (0.67) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL13153929 | 0.74 | MEN1 (0.76) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL5033202 | 0.74 | MAPT (1.00) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL5033211 | 0.74 | MAPT (1.00) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL17717644 | 0.74 | F2 (0.65) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL5594436 | 0.73 | MAPT (0.72) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL5594708 | 0.73 | MEN1 (1.00) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL12881142 | 0.73 | MEN1 (1.00) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |