Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.67 |
| ▸ | NSD2 | O96028 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 6/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CDC7 | O00311 | 1/20 | 0.59 |
| ▸ | PLK4 | O00444 | 1/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.59 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594463 | 0.82 | MEN1 (0.67) | MEN1KMT2ANSD2BLMMAPT | |
| SCHEMBL5594404 | 0.82 | APP (0.64) | MEN1KMT2ANSD2BLMMAPT | |
| SCHEMBL12881142 | 0.80 | MEN1 (1.00) | MEN1KMT2ANSD2BLMMAPT | |
| SCHEMBL5594708 | 0.80 | MEN1 (1.00) | MEN1KMT2ANSD2BLMMAPT | |
| SCHEMBL27983608 | 0.79 | MAPT (0.82) | MEN1KMT2ANSD2BLMMAPT | |
| SCHEMBL10476384 | 0.78 | THRB (0.79) | MEN1KMT2ANSD2BLMMAPT | |
| SCHEMBL21578429 | 0.78 | MAPT (0.64) | MEN1KMT2ANSD2BLMMAPT | |
| SCHEMBL12351215 | 0.77 | MAPT (0.65) | MEN1KMT2ANSD2BLMMAPT | |
| SCHEMBL5594436 | 0.75 | MAPT (0.72) | MEN1KMT2ANSD2BLMMAPT | |
| SCHEMBL10476361 | 0.75 | MAPT (0.75) | MEN1KMT2ANSD2BLMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |