Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | POLB | P06746 | 7/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | USP2 | O75604 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 0.84 |
| ▸ | MAPT | P10636 | 10/20 | 0.80 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.80 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.80 |
| ▸ | RECQL | P46063 | 1/20 | 0.80 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.80 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 2/20 | 0.76 |
| ▸ | NSD2 | O96028 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | XBP1 | P17861 | 1/20 | 0.74 |
| ▸ | CDC7 | O00311 | 1/20 | 0.70 |
| ▸ | PLK4 | O00444 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594542 | 0.89 | MAPT (1.00) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5594923 | 0.88 | MEN1 (0.78) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5594925 | 0.88 | MEN1 (0.78) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL12351294 | 0.87 | MAPT (0.83) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL12881142 | 0.86 | MEN1 (1.00) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5594708 | 0.86 | MEN1 (1.00) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL14476502 | 0.84 | MAPT (0.86) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL13153929 | 0.83 | MEN1 (0.76) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL12976217 | 0.83 | MEN1 (0.70) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL27983596 | 0.82 | MAPT (0.78) | MEN1KMT2APOLBRAB9AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |