Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.78 |
| ▸ | POLB | P06746 | 7/20 | 0.78 |
| ▸ | RAB9A | P51151 | 4/20 | 0.78 |
| ▸ | USP2 | O75604 | 4/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.78 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 12/20 | 0.65 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.65 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.65 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.65 |
| ▸ | CDC7 | O00311 | 1/20 | 0.60 |
| ▸ | PLK4 | O00444 | 1/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.60 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.60 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.60 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594923 | 1.00 | MEN1 (0.78) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL10476363 | 0.88 | MEN1 (1.00) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5594542 | 0.79 | MAPT (1.00) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5594048 | 0.78 | MAPT (0.55) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL10476367 | 0.78 | MAPT (0.55) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5594806 | 0.78 | MAPT (0.62) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5594804 | 0.78 | MAPT (0.62) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL12351294 | 0.77 | MAPT (0.83) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL14476502 | 0.75 | MAPT (0.86) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5594708 | 0.74 | MEN1 (1.00) | MEN1KMT2APOLBRAB9AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | disclosed |