Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101075 | 0.90 | GPR119 (0.53) | GPR119HDAC6DPP4HDAC4 | |
| SCHEMBL10476594 | 0.88 | GPR119 (0.54) | GPR119HDAC6HDAC1HDAC8NPY2R | |
| SCHEMBL10476567 | 0.86 | GPR119 (0.41) | GPR119HDAC6HDAC1HDAC8NPY2R | |
| SCHEMBL10476570 | 0.83 | GPR119 (0.47) | GPR119HDAC6HDAC1HDAC8NPY2R | |
| SCHEMBL10476571 | 0.82 | GPR119 (0.63) | GPR119HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL10476560 | 0.82 | GPR119 (0.63) | GPR119HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL10476559 | 0.82 | GPR119 (0.63) | GPR119HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL4412537 | 0.82 | GPR119 (0.51) | GPR119HDAC6HDAC1HDAC8DPP4 | |
| SCHEMBL10476599 | 0.81 | GPR119 (0.51) | GPR119HDAC6HDAC1HDAC8NPY2R | |
| SCHEMBL4107590 | 0.78 | GPR119 (0.69) | GPR119DPP4HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013201-B1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LTD (GB) | 2012-07-25 | — | — | EP | claimed |