Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113153 | 0.91 | GPR119 (0.48) | GPR119MAPTLMNAGPR183ALOX5AP | |
| SCHEMBL4102142 | 0.89 | GPR119 (0.45) | GPR119MAPTLMNAGPR183ALOX5AP | |
| SCHEMBL4095100 | 0.88 | GPR119 (0.55) | GPR119MAPTLMNAGPR183 | |
| SCHEMBL4106749 | 0.87 | GPR119 (0.44) | GPR119MAPTLMNAGPR183 | |
| SCHEMBL4114745 | 0.85 | GPR119 (0.43) | GPR119MAPTLMNAGPR183 | |
| SCHEMBL4114736 | 0.84 | GPR119 (0.55) | GPR119GPR183 | |
| SCHEMBL4101235 | 0.83 | GPR119 (0.50) | GPR119 | |
| SCHEMBL4112505 | 0.81 | GPR119 (0.67) | GPR119 | |
| SCHEMBL10476580 | 0.81 | GPR119 (0.43) | GPR119MAPTLMNAGPR183ALOX5AP | |
| SCHEMBL14403714 | 0.73 | GPR119 (0.57) | GPR119MAPTLMNAGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013201-B1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LTD (GB) | 2012-07-25 | — | — | EP | claimed |