Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 6/20 | 0.40 |
| ▸ | FDPS | P14324 | 9/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537975 | 1.00 | GGPS1 (0.40) | GGPS1FDPSTSHRTHRBSMPD1 | |
| SCHEMBL8654583 | 1.00 | GGPS1 (0.40) | GGPS1FDPSTSHRTHRBSMPD1 | |
| SCHEMBL7582387 | 0.90 | GGPS1 (0.43) | GGPS1FDPSTSHRTHRBSMPD1 | |
| SCHEMBL5028617 | 0.90 | FDPS (0.33) | FDPSTSHR | |
| SCHEMBL4597693 | 0.90 | GGPS1 (0.43) | GGPS1FDPSTSHRTHRBSMPD1 | |
| SCHEMBL3372046 | 0.90 | GGPS1 (0.43) | GGPS1FDPSTSHRTHRBSMPD1 | |
| SCHEMBL525489 | 0.88 | GGPS1 (0.41) | GGPS1FDPSTSHRTHRBSMPD1 | |
| SCHEMBL27639644 | 0.84 | TSHR (0.39) | GGPS1FDPSTSHRSMPD1CES2 | |
| SCHEMBL20694849 | 0.82 | GGPS1 (0.38) | GGPS1FDPSTSHRSMPD1CES2 | |
| SCHEMBL502512 | 0.79 | FDPS (0.36) | GGPS1FDPSTSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4825008-A | Acetylketene dialkyl acetals and a process for their preparation | HOESCHST AKTIENGESELLSCHAFT (DE) | 1989-04-25 | — | — | US | disclosed |