Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.62 |
| ▸ | HTR1A | P08908 | 5/20 | 0.62 |
| ▸ | HTR2A | P28223 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HTR2B | P41595 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | BLM | P54132 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.62 |
| ▸ | HTR7 | P34969 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688689 | 1.00 | HTR2C (0.62) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL3688690 | 1.00 | HTR2C (0.62) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL10477283 | 1.00 | HTR2C (0.62) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL3688692 | 1.00 | HTR2C (0.62) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL11726522 | 0.84 | HTR2C (0.66) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL10701712 | 0.84 | HTR2C (0.66) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL10701707 | 0.84 | HTR2C (0.66) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL28069324 | 0.81 | HTR2C (0.63) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL21594207 | 0.81 | HTR2C (0.62) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL8246464 | 0.79 | HTR2C (0.74) | HTR2CNPSR1HTR1AHTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822812-A | ANTIDEPRESSANT-MONOAMINE OXIDASE INHIBITOR | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0291998-A2 | Beta-(fluoromethylene)-5-hydroxytryptophan and derivatives as prodrugs for mao inhibition | MERRELL PHARMACEUTICALS INC. (US) | 1988-11-23 | — | — | EP | disclosed |