Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.63 |
| ▸ | HTR1A | P08908 | 5/20 | 0.63 |
| ▸ | HTR2A | P28223 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HTR2B | P41595 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.63 |
| ▸ | HTR7 | P34969 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701707 | 0.85 | HTR2C (0.66) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL11726522 | 0.85 | HTR2C (0.66) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL10701712 | 0.85 | HTR2C (0.66) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL30661929 | 0.83 | SMN1; SMN2 (0.62) | ALDH1A1KDM4ELMNATSHRBLM | |
| SCHEMBL27367040 | 0.83 | SMN1; SMN2 (0.62) | ALDH1A1KDM4ELMNATSHRBLM | |
| SCHEMBL3688690 | 0.81 | HTR2C (0.62) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL3688689 | 0.81 | HTR2C (0.62) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL21594207 | 0.81 | HTR2C (0.62) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL10477283 | 0.81 | HTR2C (0.62) | HTR2CNPSR1HTR1AHTR2AALDH1A1 | |
| SCHEMBL10477282 | 0.81 | HTR2C (0.62) | HTR2CNPSR1HTR1AHTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636438-A | Pharmaceutical composition comprising an AMPK activator and a serotonin active agent and uses thereof | CHEN JIANHONG | 2016-06-01 | — | — | CN | claimed |