Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 4/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10477703 | 0.99 | REN (0.33) | RENPSMB5CTSDMMP1MMP3 | |
| Hydrochloric Acid SCHEMBL10477759 | 0.99 | REN (0.33) | RENPSMB5CTSDMMP1MMP3 | |
| Hydrochloric Acid SCHEMBL10477780 | 0.89 | REN (0.40) | REN | |
| Hydrochloric Acid SCHEMBL10477793 | 0.86 | REN (0.33) | REN | |
| Hydrochloric Acid SCHEMBL10477671 | 0.84 | REN (0.34) | REN | |
| Hydrochloric Acid SCHEMBL10477741 | 0.84 | IL1RN (0.34) | RENCTSD | |
| Hydrochloric Acid SCHEMBL10477681 | 0.84 | IL1RN (0.34) | RENCTSD | |
| SCHEMBL11124947 | 0.82 | NPSR1 (0.40) | REN | |
| SCHEMBL29473464 | 0.80 | REN (0.43) | RENCTSD | |
| SCHEMBL7277204 | 0.79 | HSPA5 (0.36) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4857650-A | Novel renin inhibitory amino acid derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |